Human IL3- Recombinant (AF)

IL-3 acts as a crucial hematopoietic growth factor, supporting the survival, differentiation, and proliferation of specialized progenitor cells spanning various lineages such as megakaryocytes, granulocyte-macrophages, erythrocytes, eosinophils, basophils, and mast cells. It is produced by T cells, mast cells, and eosinophils, contributing significantly to processes like thrombopoiesis, phagocytosis, and antibody-mediated cellular cytotoxicity. IL-3 also triggers monocyte activation, suggesting potential additional roles in immunoregulation. Many of its effects hinge on co-stimulation with other cytokines. Notably, IL-3 shows species-specific variability in glycosylation patterns. The recombinant Human IL-3 is a 15.0 kDa globular protein comprising 133 amino acid residues.